Lottes verden forandres for altid, da familien flytter langt væk fra alt det, hun kender. Ensomheden truer, indtil hun møder den energiske nabodreng Totte. Men da en af deres fantasifulde lege går for vidt, bliver de mega meget uvenner. Lotte indser, at Totte er hendes første rigtige ven og vil gøre alt for at genvinde venskabet, før det er for sent.
When Lotte’s world is turned upside down by a big family move, she’s left feeling lost and lonely. Just as she is about to give up all hope for new friends, she meets Totte—the energetic neighbor boy who makes life exciting again. But one day, she takes things too far in one of their creative games, and their friendship is ruined. Lotte must now find all of her courage to make things right. “Lotte & Totte” is a heartwarming, feel-good animated story about the first true friendship and how life is not always easy when you experience everything for the first time.